Vitamin B12 / Cyanocobalamin      (Page 1)

Vitamin B12 / Cyanocobalamin    (Page 1)

Excerpt from and my appreciation to:
The Columbia Encyclopedia, Sixth Edition.  2001.*
*If viewed at above web-page linked above, scroll down to section #16 to see Vitamin B12 ...

"Vitamin:  A group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction..."

Vitamin B12
The molecular structure of vitamin B12 vitamin. B12 (cobalamin), the most complex of all known vitamins, was announced in 1955 by several scientists, including British biochemists A. R. Todd and Dorothy Hodgkin. In 1973 the vitamin was reported to have been synthesized by organic chemists. Vitamin B12 and closely related cobalamins are necessary for folic acid to fulfill its role; both are involved in the synthesis of proteins. American physicians G. R. Minot and W. P. Murphy in 1926 fed large amounts of liver to patients with pernicious anemia and cured them; the curative substance in this case was probably vitamin B12. However, pernicious anemia in humans is caused not by a vitamin B12 deficiency in the diet but rather the absence of a substance called the intrinsic factor, ordinarily secreted by the stomach and responsible for facilitating the absorption of B12 from the intestine. When a person's body cannot produce the intrinsic factor, the standard treatment today is to inject vitamin B12 directly into the bloodstream. Minot and Murphy’s therapy worked because the liver they fed their patients contained such large quantities of B12 that sufficient amounts of the vitamin were absorbed without the assistance of the intrinsic factor. Inadequate absorption of B12 causes pernicious anemia, nervous system degeneration, and amenorrhea. The only site of cobalamin synthesis in nature appears to be in microorganisms*; neither animals nor higher plants are capable of making these vitamin B12 derivatives. Nevertheless, such animal tissues as the liver, kidney, and heart of ruminants contain relatively large quantities of vitamin B12; the vitamin stored in these organs was originally produced by the (Cyano-) bacteria (and is absorbed) in the ruminant gut. Bivalves (clams or oysters), which siphon microorganisms* from the sea, are also good sources. Plants, on the other hand, are poor sources of (concentrated)** vitamin B12. The recommended daily dietary allowance for adults is 3 micrograms (3 micrograms? - see all that is written below).

My notes and added information for understanding the statement of facts above:

* Cyanocobalamin - Vitamin B12 producing bacteria are in the Cyanobacterium (algae, moses) family. This class of microorganisms are the bacteria that generally require and live in the sunlight and/or oxygenated environment of the plant surfaces, roots, upper soils and in the waters (near surface). They do not survive in the black dark anaerobic environment of interior animal tissues -- though their exo- and endo-compounds (metabolic excretions), including the vitamin B12 compound group, do remain viable and is accumulated and concentrated in the herbivorous (plant material consuming) animals (in fecal material, intestines, hence is delivered into all body tissues, blood, muscles, entrails, esp. liver and kidneys) and is also expressed, i.e. transported out (to manage internal tissue levels) through and in body fluids (milk, mucus, urine) or ova (eggs). 

There is some presumptions of data that pro ports they (Cyanocobalamin bacteria) have some survival and production activity in the (dissolved oxygen and plant nutrient available) gut (primarily gullet and lower intestine) of herbivores / ruminants (e.g. cow, goat, horse, etc.) animals.  But it is well understood that the critically important source of B12 in livestock (gen. ruminant) production is in their feeds (unwashed, untreated) silage (corn, grains, beet pulp, ferments) along with alfalfa and hay -- where these plant loving cyano-bacteria flourish, then enter into the consuming animal!

(concentrated**) -- my insertion to the Columbia Encyclopedia's text, 2nd to last line above.
God and nature has made no mistakes in providing sufficient Vitamin B12 to billions of herbivorous animals over millions of millennia - including the vegetarian primates (our biologically nearest creational equivalents) and man! -- if he (man) makes the right dietary choices and nourishes himself the way he was originally designed! -- That is: In and from the garden! -- the perfect home of pure, uncontaminated, light, oxygen and vegetation loving Cyanocobalamin, in correct bounty, in low concentrations, but sufficient for our needs!-- Not extorted from defiled, destroyed, killed, disease hosting, disease transmitting and B12 hyper-concentrating animals -- especially carnivorous animals (as poultry, pork, fish, etc.), which accumulate and concentrate even more B12 in their tissue, fluids and ova at levels above and higher than the herbivorous animals and/or the insects which they consume. Hence carnivores (including man when he chooses to be such) do ultra-concentrate B12 in their tissues! 

Hence in carnivorous man, a falsely high mean standard of B12 levels is accumulated and is consequently measured high in phlebotomy data; so it is accepted as the human norm! -- Not good or honest science!!! 

And that false high standard (as has been accepted by most all of medicine) precipitates wrong diagnosis! that is, lower test values of accumulatedserum*** B12 levels -- which are naturally (and correctly) less in non-carnivorous (vegetarian) humans and their dependent nursing infants! Those presumed "deficient" patients are then endangered with the unnecessary administrations of (the sewage and/or animal harvested and unnaturally formulated) B12 injections and/or tablets, with their plethora of contraindications (side affects) possible in many recipient patients or wrongly treated victims!

*** serum (blood stream) levels of B12 is not always a good indication of true internal, intra-/inter-cellular, metabolic, B12 functional levels. It is also (now) known that the cells are ultra conservative with B12; i.e. keeping appropriate stores of it within the cells themselves, recycling it within the intra-cellular (inside) chemistry and allowing only that which is absolutely necessary in inter-cellular (between cells) chemistry to be exported, hence not requiring (as was previously presumed) high levels of B12 to be carried in consumption, digestion, absorption and blood flow to replenish it.  -- tlr 7/3/03

Standard medicine has seriously erred in the violation of honored Koch postulates and true scientific method, by producing unnatural high average blood level standards for B12, and assuming them as the correct human  mean or standard  -- based upon hematological data accumulated and calculated in the cross-section of primarily heavily carnivorous USA/Industrial world humans! -- not a true or honest measure for serum B12 levels for all of humanity, nor for creation's biologically intended, apparent and correct human nutrition, chemistry and physiology! 

The original concern over Vitamin B12 deficiency (based on research started more than three quarters of a century ago and completed over a half century ago) was a perceived relationship in poor health conditions called "pernicious anima" (and other closely related neurological and physiological malfunctions). It now has been established that the true cause of this group of maladies is a  failure in the bodies own ability to produce its own correct "intrinsic factor", a compound associated with B12's intra/intercellular transport and use -- which is ill-formed  in a hydrochloric acid and a bile abused (a condition specifically triggered by the corrosive digestion requirements for complex, high molecular weight, dense animal fats and proteins within a) malnourished, malfunctioning, or chemically damaged (or more rarely, genetically flawed) intestinal tract -- rather than the old belief that the cause was (as presumed) a Vitamin B12 intake or (a test determined*) serum level deficiency! 
*Remember, these test protocols and standards were determined over a half century year ago, and also were based on generally highly carnivorous, western human models.

 -- This error in perception, diagnoses and treatment does persist, even to date among too many non-current or incompletely educated health practitioners, their older peers,  administrations and dependent government health and welfare agencies! -- tlr 7/2/03

Personal references: Veterinary & Human Biology & Pathology education and reference books / personal Human, Animal, Livestock and Marine (algae) research and experience -- and personally required knowledge for good livestock production and profit -- in my past.

I will try to improve upon and expand this page later as my resources/time allow. In the meantime, you may see a reference to intestinal (microvilli) repair at, and other intestine and whole body healing and nutritional information on, and our other subject specific sites (listed on and
TLR. 7/1/03

(Questions? - call me. 801-298-9095, active Caller ID required, displayed and recorded, or Email or mail PO Box 304 Bountiful Utah 84011-0304)
Please now go to Page Two: "The Rest of the Vitamin B12 Story!"
 Intrinsic Factor Production, Absorption, Wasting Problems, etc! 
 - Click here! (to my subsequent draft developed as an answer to another Dr's personal inquiry)

Appreciation to my wife and family
Constructing this page has taken more than three full days away from family and real income producing work (which also goes to cover this labors total direct costs including the necessary ongoing internet debts). This required the confirming in all my old references, personal texts, notes and data from forty years education and experience back; then the time and concentration to ponder, recheck my supporting data, organize, write, edit, rewrite re-edit -- and I am probably still not finished with refining it for you!  My hope is you will be benefited, have correct knowledge, prove it yourself as is possible, and that you will appreciate this labor and sacrifice (especially that which affects and leaves my family short) given for you, the reader! 
Click to Contributions pageAny donation to help maintain this effort in return for your benefited health would be appropriate and appreciated --  tlr
Page created July 1, 03. Last edit Dec 11 2004.  Visitors since counter reset Nov 5, 03.
... . B12 page 2 . Manufactures data. Pathophysiology Text: 194-6 . 215-6 . 470-2 . Letter
 See case: Family Vs State &  Medical error over Vitamin B12! -- The senseless bases for nursing baby's removal:
His Mom's blood & milk levels. - Any struggling infant's best form and supply!!!  in